Associate Professor Luregn Schlapbach

Gc, Vijay S., Franklin, Donna, Whitty, Jennifer A., Dalziel, Stuart R., Babl, Franz E., Schalpbach, Luregn J., Fraser, John F., Craig, Simon, Neutze, Jocelyn, Oakley, Ed and Schibler, Andreas (2020). First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service. Archives of Disease in Childhood, 105 (10), 975-980. doi: 10.1136/archdischild-2019-318427

Schlapbach, Luregn J., Kissoon, Niranjan, Alhawsawi, Abdulelah, Aljuaid, Maha H., Daniels, Ron, Gorordo-Delsol, Luis A., Machado, Flavia, Malik, Imrana, Nsutebu, Emmanuel Fru, Finfer, Simon and Reinhart, Konrad (2020). World Sepsis Day: a global agenda to target a leading cause of morbidity and mortality. American Journal of Physiology-Lung Cellular and Molecular Physiology, 319 (3), L518-L522. doi: 10.1152/ajplung.00369.2020

Raman, Sainath, Tai, Chian Wern, Le Marsney, Renate, Schibler, Andreas, Gibbons, Kristen and Schlapbach, Luregn J. (2020). Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care. Pediatric Critical Care Medicine, Publish Ahead of Print (9), 811-819. doi: 10.1097/pcc.0000000000002411

Moynihan, Katie M., McGarvey, Tambra, Barlow, Andrew, Heney, Claire, Gibbons, Kristen, Clark, Julia E., Schlebusch, Sanmarié and Schlapbach, Luregn J. (2020). Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 21 (6), 1-e341. doi: 10.1097/PCC.0000000000002302

Schlapbach, Luregn J., Chiletti, Roberto, Straney, Lahn, Festa, Marino, Alexander, Daniel, Butt, Warwick and MacLaren, Graeme (2019). Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study. Critical Care, 23 (1) 429, 429. doi: 10.1186/s13054-019-2685-1

Wang, Xinzhu, Nijman, Ruud, Camuzeaux, Stephane, Sands, Caroline, Jackson, Heather, Kaforou, Myrsini, Emonts, Marieke, Herberg, Jethro A., Maconochie, Ian, Carrol, Enitan D., Paulus, Stephane C., Zenz, Werner, Van der Flier, Michiel, de Groot, Ronald, Martinon-Torres, Federico, Schlapbach, Luregn J., Pollard, Andrew J., Fink, Colin, Kuijpers, Taco T., Anderson, Suzanne, Lewis, Matthew R., Levin, Michael, McClure, Myra and & EUCLIDS consortium (2019). Plasma lipid profiles discriminate bacterial from viral infection in febrile children. Scientific Reports, 9 (1) 17714, 17714. doi: 10.1038/s41598-019-53721-1

Schlapbach, Luregn J., Horton, Stephen Brian, Long, Debbie Amanda, Beca, John, Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Winlaw, David, Johnson, Kerry, Delzoppo, Carmel, van Loon, Kim, Gannon, B., Fooken, Jonas, Blumenthal, Antje, Young, Paul, Jones, Mark, Butt, Warwick and Schibler, Andreas (2019). Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial. BMJ Open, 9 (8) e026664, e026664. doi: 10.1136/bmjopen-2018-026664

Farrell, Deborah, MacLaren, Graeme and Schlapbach, Luregn J. (2019). Infections on extracorporeal life support in adults and children-a survey of international practice on prevention, diagnosis, and treatment. Pediatric Critical Care Medicine, 20 (7), 667-671. doi: 10.1097/PCC.0000000000001941

Borghini, Lisa, Png, Eileen, Binder, Alexander, Wright, Victoria J., Pinnock, Ellie, de Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van der Flier, Michiel, Schlapbach, Luregn J., Anderson, Suzanne, Secka, Fatou, Salas, Antonio, Fink, Colin, Carrol, Enitan D., Pollard, Andrew J., Coin, Lachlan J., Kuijpers, Taco W., Martinon-Torres, Federico, Zenz, Werner, Levin, Michael, Hibberd, Martin L., Davila, Sonia and EUCLIDS consortium (2019). Identification of regulatory variants associated with genetic susceptibility to meningococcal disease. Scientific Reports, 9 (1) 6966, 6966. doi: 10.1038/s41598-019-43292-6

Schlapbach, Luregn J., Gelbart, Ben, Gelbart, Ben, Festa, Marino, The Australian & New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), Kanthimathinathan, Hari Krishnan, Peters, M. J. and Long, Debbie (2019). Global paediatric critical care research: mind the gaps. Intensive Care Medicine, 45 (5), 753-754. doi: 10.1007/s00134-019-05571-8

Schlapbach, Luregn J. and Argent, Andrew (2019). Applying Sepsis-3 criteria for septic shock to children-not as shocking as at first sight?*. Pediatric Critical Care Medicine, 20 (3), 299-300. doi: 10.1097/PCC.0000000000001884

George, Shane, Humphreys, Susan, Williams, Tara, Gelbart, Ben, Chavan, Arjun, Rasmussen, Katie, Ganeshalingham, Anusha, Erickson, Simon, Ganu, Subodh Suhas, Singhal, Nitesh, Foster, Kelly, Gannon, Brenda, Gibbons, Kristen, Schlapbach, Luregn J, Festa, Marino, Dalziel, Stuart and Schibler, Andreas (2019). Transnasal humidified rapid insufflation ventilatory exchange in children requiring emergent intubation (Kids THRIVE): a protocol for a randomised controlled trial. BMJ Open, 9 (2) e025997, e025997. doi: 10.1136/bmjopen-2018-025997

McKenna, Ronan, Joseph, Lindsay, Sargent, Philip, May, Meryta, Tozer, Sarah, Bialasiewicz, Seweryn, Heney, Claire, Schlapbach, Luregn J. and Clark, Julia E. (2019). Paediatric intensive care admissions during the 2015-2016 Queensland human parechovirus outbreak: parechovirus intensive care admissions. Journal of Paediatrics and Child Health, 55 (8), 968-974. doi: 10.1111/jpc.14336

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425

Moynihan, Katie M., Barlow, Andrew, Heney, Claire, Clark, Julia E., Schlebusch, Sanmarie and Schlapbach, Luregn J. (2019). Viral respiratory infections diagnosed after PICU admission. Pediatric Critical Care Medicine, 20 (1), E46-E50. doi: 10.1097/PCC.0000000000001757

Moynihan, Katie M., Barlow, Andrew, Nourse, Clare, Heney, Claire, Schlebusch, Sanmarié and Schlapbach, Luregn J. (2018). Severe Mycoplasma Pneumoniae Infection in Children Admitted to Pediatric Intensive Care. The Pediatric infectious disease journal, 37 (12), e336-e338. doi: 10.1097/INF.0000000000002029

Dierig, Alexa, Berger, Christoph, Agyeman, Philipp K. A., Bernhard-Stirnemann, Sara, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Hasters, Paul, Relly, Christa, Riedel, Thomas, Aebi, Christoph, Schlapbach, Luregn J. and Heininger, Ulrich (2018). Time-to-positivity of blood cultures in children with sepsis. Frontiers in Pediatrics, 6 222, 222. doi: 10.3389/fped.2018.00222

Giannoni, Eric, Agyeman, Philipp K. A., Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Spycher, Ben D., Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Riedel, Thomas, Kuehni, Claudia, Aebi, Christoph, Berger, Christoph, Schlapbach, Luregn J. and Swiss Pediatric Sepsis Study (2018). Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study. The Journal of Pediatrics, 201, 106-114.e4. doi: 10.1016/j.jpeds.2018.05.048

Perumal, Gopinath, Marathe, Supreet P., Schlapbach, Luregn J., Morwood, Jim, Venugopal, Prem and Alphonso, Nelson (2018). Postoperative catecholamine resistance following fetal methamphetamine exposure. Asian Cardiovascular & Thoracic Annals, 27 (1), 218492318784740-32. doi: 10.1177/0218492318784740

Gelbart, Ben, Schlapbach, Luregn, Ganeshalingham, Anusha, Ganu, Subodh, Erickson, Simon, Oberender, Felix, Hoq, Monsurul, Williams, Gary, George, Shane, Festa, Marino, Paediatric Study Group of the Australian and New Zealand Intensive Care Society and Long, Debbie (2018). Fluid bolus therapy in critically ill children: a survey of practice among paediatric intensive care doctors in Australia and New Zealand. Critical Care and Resuscitation, 20 (2), 131-138.

Schlapbach, Luregn J., Berger, Christoph, Aebi, Christoph and Agyeman, Philipp K.A. (2018). SIRS in the time of sepsis-3: what about the children?. Chest, 153 (6), 1512-1512. doi: 10.1016/j.chest.2018.02.037

Kawasaki, Tatsuya, Shime, Nobuaki, Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme, Pilcher, David and Schlapbach, Luregn J. (2018). Paediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus. Intensive Care Medicine, 44 (6), 995-997. doi: 10.1007/s00134-018-5188-7

Martinón-Torres, Federico, Salas, Antonio, Rivero-Calle, Irene, Cebey-López, Miriam, Pardo-Seco, Jacobo, Herberg, Jethro A, Boeddha, Navin P, Klobassa, Daniela S, Secka, Fatou, Paulus, Stephane, de Groot, Ronald, Schlapbach, Luregn J, Driessen, Gertjan J, Anderson, Suzanne T, Emonts, Marieke, Zenz, Werner, Carrol, Enitan D, Van der Flier, Michiel, Levin, Michael, Levin, Michael, Coin, Lachlan, Gormley, Stuart, Hamilton, Shea, Herberg, Jethro, Hourmat, Bernardo, Hoggart, Clive, Kaforou, Myrsini, Sancho-Shimizu, Vanessa, Wright, Victoria ... EUCLIDS Consortium (2018). Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study. The Lancet Child and Adolescent Health, 2 (6), 404-414. doi: 10.1016/S2352-4642(18)30113-5

Jansen, Melanie A., Schlapbach, Luregn J. and Irving, Helen (2018). Evaluation of a paediatric clinical ethics service. Journal of Paediatrics and Child Health, 54 (11), 1199-1205. doi: 10.1111/jpc.13933

Leclerc, Francis, Duhamel, Alain, Leteurtre, Stéphane, Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme, Pilcher, David and Schlapbach, Luregn J. (2018). Which organ dysfunction scores to use in children with infection?. Intensive Care Medicine, 44 (5), 697-698. doi: 10.1007/s00134-018-5123-y

Franklin, Donna, Babl, Franz E, Schlapbach, Luregn J, Oakley, Ed, Craig, Simon, Neutze, Jocelyn, Furyk, Jeremy, Fraser, John F, Jones, Mark, Whitty, Jennifer A, Dalziel, Stuart R. and Schibler, Andreas (2018). A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. New England Journal of Medicine, 378 (12), 1121-1131. doi: 10.1056/NEJMoa1714855

Fleischmann-Struzek, Carolin, Goldfarb, David M., Schlattmann, Peter, Schlapbach, Luregn J., Reinhart, Konrad and Kissoon, Niranjan (2018). The global burden of paediatric and neonatal sepsis: a systematic review. The Lancet Respiratory Medicine, 6 (3), 223-230. doi: 10.1016/S2213-2600(18)30063-8

Domico, Michele, Ridout, Deborah, MacLaren, Graeme, Barbaro, Ryan, Annich, Gail, Schlapbach, Luregn J. and Brown, Katherine L. (2018). Extracorporeal membrane oxygenation for pertussis: predictors of outcome including pulmonary hypertension and leukodepletion. Pediatric Critical Care Medicine, 19 (3), 254-261. doi: 10.1097/PCC.0000000000001454

Schlapbach, Luregn J. and Kissoon, Niranjan (2018). Defining pediatric sepsis. JAMA Pediatrics, 172 (4), 312-314. doi: 10.1001/jamapediatrics.2017.5208

Buettcher, M., Schlapbach, L. J. and Stocker, M. (2018). Sepsis in children—completely different? Sepsis bei Kindern – alles anders?. Notfall und Rettungsmedizin, 22 (3), 219-225. doi: 10.1007/s10049-018-0506-8

Schlapbach, Luregn J., Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme and Pilcher, David (2017). Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit. Intensive Care Medicine, 44 (2), 179-188. doi: 10.1007/s00134-017-5021-8

Maul, Clark P., Franklin, Donna, Williams, Tara, Schlapbach, Luregn and Schibler, Andreas (2017). Nasal high-flow therapy in children: a survey of current practice in Australia. Journal of Paediatrics and Child Health, 53 (10), 1031-1032. doi: 10.1111/jpc.13695

Agyeman, Philipp, Schlapbach, Luregn J., Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Schindler, Matthias, Korten, Insa, Konetzny, Gabriel, Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Baer, Walter, Kuehni, Claudia E., Aebi, Christoph and Berger, Christoph (2017). Epidemiology of blood culture-proven bacterial sepsis in children in Switzerland: a prospective population-based cohort study. The Lancet Child and Adolescent Health, 1 (2), 124-133. doi: 10.1016/S2352-4642(17)30010-X

Kessler, Ulf, Schlapbach, Luregn J., Klimek, Peter and Jakob, Stephan M. (2017). Low L-Ficolin associated with disease severity during sepsis in adult ICU patients. Liver International, 37 (9), 1409-1409. doi: 10.1111/liv.13448

Schlapbach, Luregn J. (2017). Time for sepsis-3 in children?. Pediatric Critical Care Medicine, 18 (8), 805-806. doi: 10.1097/PCC.0000000000001203

Schlapbach, Luregn J., MacLaren, Graeme and Straney, Lahn (2017). Venous vs arterial lactate and 30-day mortality in pediatric sepsis. JAMA Pediatrics, 171 (8), 813-813. doi: 10.1001/jamapediatrics.2017.1598

Asgari, Samira, Schlapbach, Luregn J., Anchisi, Stéphanie, Hammer, Christian, Bartha, Istvan, Junier, Thomas, Mottet-Osman, Geneviève, Posfay-Barbe, Klara M., Longchamp, David, Stocker, Martin, Cordey, Samuel, Kaiser, Laurent, Riedel, Thomas, Kenna, Tony, Long, Deborah, Schibler, Andreas, Telenti, Amalio, Tapparel, Caroline, McLaren, Paul J., Garcin, Dominique and Fellay, Jacques (2017). Severe viral respiratory infections in children with IFIH1 loss-of-function mutations. Proceedings of the National Academy of Sciences, 114 (31), 8342-8347. doi: 10.1073/pnas.1704259114

Schlapbach, Luregn J., Ostrowski, Justyna A. and MacLaren, Graeme (2017). The excess burden of severe sepsis in Indigenous Australian children: can anything be done?. Medical Journal of Australia, 207 (1), 45-46. doi: 10.5694/mja17.00464

Schlapbach, Luregn J., Straney, Lahn, Gelbart, Ben, Alexander, Janet, Franklin, Donna, Beca, John, Whitty, Jennifer A., Ganu, Subodh, Wilkins, Barry, Slater, Anthony, Croston, Elizabeth, Erickson, Simon and Schibler, Andreas (2017). Burden of disease and change in practice in critically ill infants with bronchiolitis. European Respiratory Journal, 49 (6) 1601648, 1601648. doi: 10.1183/13993003.01648-2016

Schlapbach, Luregn J., Javouhey, Etienne and Jansen, Nicolaas J. G. (2017). Paediatric sepsis: old wine in new bottles?. Intensive Care Medicine, 43 (11), 1-4. doi: 10.1007/s00134-017-4800-6

Schlapbach, Luregn J. and MacLaren, Graeme (2017). Targeting Staphylococcus aureus in pediatric surviving sepsis bundles. JAMA Pediatrics, 171 (3), 301-301. doi: 10.1001/jamapediatrics.2016.4675

Schlapbach, Luregn J., MacLaren, Graeme, Festa, Marino, Alexander, Janet, Erickson, Simon, Beca, John, Slater, Anthony, Schibler, Andreas, Pilcher, David, Millar, Johnny and Straney, Lahn (2017). Prediction of pediatric sepsis mortality within 1 h of intensive care admission. Intensive Care Medicine, 43 (8), 1085-1096. doi: 10.1007/s00134-017-4701-8

Ostrowski, Justyna A., Maclaren, Graeme, Alexander, Janet, Stewart, Penny, Gune, Sheena, Francis, Joshua R., Ganu, Subodh, Festa, Marino, Erickson, Simon J., Straney, Lahn and Schlapbach, Luregn J. (2017). The burden of invasive infections in critically ill indigenous children in Australia. Medical Journal of Australia, 206 (2), 78-84. doi: 10.5694/mja16.00595

Roger, Thierry, Schlapbach, Luregn J., Schneider, Anina, Weier, Manuela, Wellmann, Sven, Marquis, Patrick, Vermijlen, David, Sweep, Fred C. G. J., Leng, Lin, Bucala, Richard, Calandra, Thierry and Giannoni, Eric (2017). Plasma levels of macrophage migration inhibitory factor and d-dopachrome tautomerase show a highly specific profile in early life. Frontiers in Immunology, 8 (JAN) 26, 26. doi: 10.3389/fimmu.2017.00026

Moynihan, Katie, Barlow, Andrew, Alphonso, Nelson, Anderson, Ben, Johnson, Janelle, Nourse, Clare, Schlebusch, Sanmarié, Karl, Tom R. and Schlapbach, Luregn J. (2017). Impact of viral respiratory pathogens on outcomes after pediatric cardiac surgery. Pediatric Critical Care Medicine, 18 (3), 219-227. doi: 10.1097/PCC.0000000000001083

Mattke, Adrian C., Prabhu, Sudesh, Clark, Julia, Labrom, Robert, Burns, Hanna and Schlapbach, Luregn J. (2017). Lemierre's syndrome, necrotizing pneumonia and staphylococcal septic shock treated with extracorporeal life support. Sage Open Medical Case Reports, 5, 1-5. doi: 10.1177/2050313X17722726

Morin, Luc, Ray, Samiran, Wilson, Clare, Remy, Solenn, Benissa, Mohamed Rida, Jansen, Nicolaas J. G., Javouhey, Etienne, Peters, Mark J., Kneybar, Martin, De Luca, Daniele, Nadel, Simon, Schlapback, Luregn Jan, Maclaren, Graeme and Tissieres, Pierre (2016). Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition. Intensive Care Medicine, 42 (12), 1-10. doi: 10.1007/s00134-016-4574-2

Asgari, Samira, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Kyra A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Lurgen J. and Swiss Pediatric Sepsis Study (2016). Corrigendum: exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis. Frontiers in immunology, 7 (OCT) 447, 447. doi: 10.3389/fimmu.2016.00447

Asgari, Samari, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Krya A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Luregn, J., Posfay-Barbe, Klara, Giannoni, Eric, Wagner, Benedicht P., Heininger, Ulrich, Konetzny, Gabriel, Donas, Alex, Stocker, Martin, Leone, Antonio, Hasters, Paul, Niederer-Loher, Anita, Kahlert, Christian, Baer, Walter and Relly, Christa (2016). Exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis. Frontiers in Immunology, 7 (SEP) 357, 357. doi: 10.3389/fimmu.2016.00357

Straney, Lahn, Schibler, Andreas, Ganeshalingham, Anusha, Alexander, Janet, Festa, Marino, Slater, Anthony, Maclaren, Graeme and Schlapbach, Luregn J. (2016). Burden and outcomes of severe pertussis infection in critically ill infants. Pediatric Critical Care Medicine, 17 (8), 735-742. doi: 10.1097/PCC.0000000000000851

Zant, Robert, Stocker, Christian, Schlapbach, Luregn Jan, Mayfield, Sara, Karl, Tom and Schibler, Andreas (2016). Procalcitonin in the early course post pediatric cardiac surgery. Pediatric Critical Care Medicine, 17 (7), 624-629. doi: 10.1097/PCC.0000000000000751

van Herk, Wendy, el Helou, Salhab, Janota, Jan, Hagmann, Cornelia, Klingenberg, Claus, Staub, Eveline, Giannoni, Eric, Tissieres, Pierre, Schlapbach, Luregn J., van Rossum, Annemarie M. C., Pilgrim, Sina B. and Stocker, Martin (2016). Variation in current management of term and late-preterm neonates at risk for early-onset sepsis: an international survey and review of guidelines. Pediatric Infectious Disease Journal, 35 (5), 494-500. doi: 10.1097/INF.0000000000001063

Giannoni, Eric, Berger, Christoph, Stocker, Martin, Agyeman, Philipp, Posfay-Barbe, Klara M., Heininger, Ulrich, Konetzny, Gabriel, Niederer-Loher, Anita, Kahlert, Christian, Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Baer, Walter, Aebi, Christoph, Schlapbach, Luregn J. and for the Swiss Pediatric Sepsis Study Group (2016). Incidence and outcome of Group B streptococcal sepsis in infants in Switzerland. Pediatric Infectious Disease Journal, 35 (2), 222-224. doi: 10.1097/INF.0000000000000974

Schlapbach, Luregn J., Giannoni, Eric, Wellmann, Sven, Stocker, Martin, Ammann, Roland A. and Graf, Rolf (2015). Normal values for pancreatic stone protein in different age groups. BMC Anesthesiology, 15 (1) 168, 1-6. doi: 10.1186/s12871-015-0149-y

Franklin, Donna, Dalziel, Stuart, Schlapbach, Luregn J., Babl, Franz E., Oakley, Ed, Craig, Simon S., Furyk, Jeremy S., Neutze, Jocelyn, Sinn, Kam, Whitty, Jennifer A., Gibbons, Kristen, Fraser, John and Schibler, Andreas (2015). Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): A Paediatric Acute Respiratory Intervention Study (PARIS). BMC Pediatrics, 15 (1) 183, 183.1-183.8. doi: 10.1186/s12887-015-0501-x

Namachivayam, Siva P., Alexander, Janet, Slater, Anthony, Millar, Johnny, Erickson, Simon, Tibballs, James, Festa, Marino, Ganu, Subodh, Segedin, Liz, Schlapbach, Luregn J., Williams, Gary, Shann, Frank and Butt, Warwick (2015). Five-year survival of children with chronic critical illness in Australia and New Zealand. Critical care medicine, 43 (9), 1978-1985. doi: 10.1097/CCM.0000000000001076

Straney, Lahn D., Schlapbach, Luregn J., Yong, Glenn, Bray, Janet E., Millar, Johnny, Slater, Anthony, Alexander, Janet, Finn, Judith and for the Australian and New Zealand Intensive Care Society Paediatric Study Group (2015). Trends in PICU admission and survival rates in children in Australia and New Zealand following cardiac arrest. Pediatric Critical Care Medicine, 16 (7), 613-620. doi: 10.1097/PCC.0000000000000425

Schlapbach, Luregn J., Straney, Lahn, Alexander, Janet, MacLaren, Graeme, Festa, Marino, Schibler, Andreas and Slater, Anthony (2015). Mortality related to invasive infections, sepsis, and septic shock in critically ill children in Australia and New Zealand, 2002-13: a multicentre retrospective cohort study. The Lancet Infectious Diseases, 15 (1), 46-54. doi: 10.1016/S1473-3099(14)71003-5

Keizer, M. P., Wouters, D., Schlapbach, L. J. and Kuijpers, T. W. (2014). Restoration of MBL-deficiency: redefining the safety, efficacy and viability of MBL-substitution therapy. Molecular Immunology, 61 (2), 174-184. doi: 10.1016/j.molimm.2014.06.005

Larcombe, P. J., Kapur, N., Fraser, C. J., Coulthard, M. G. and Schlapbach, L. J. (2014). Intrabronchial Administration of Activated Recombinant Factor VII in a Young Child With Diffuse Alveolar Hemorrhage. Pediatric Blood & Cancer, 61 (3), 570-571. doi: 10.1002/pbc.24841

Schlapbach, Luregn J., Schaefer, Jonas, Brady, Ann-Maree, Mayfield, Sara and Schibler, Andreas (2014). High-flow nasal cannula (HFNC) support in interhospital transport of critically ill children. Intensive Care Medicine, 40 (4), 592-599. doi: 10.1007/s00134-014-3226-7

Schlapbach, Luregn J., Ersch, Joerg, Balmer, Christian, Pretre, Rene, Tomaske, Maren, Caduff, Rosmarie, Morwood, Jim, Provenzano, Sylvio and Stocker, Christian (2013). Enteroviral myocarditis in neonates. Journal of Paediatrics and Child Health, 49 (9), E451-E454. doi: 10.1111/jpc.12248

Amman, Roland A., Bodmer, Nicole, Simon, Arne, Agyeman, Philipp, Leibundgut, Kurt, Schlapbach, Luregn J. and Niggli, Felix K. (2013). Serum concentrations of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the risk of adverse events in pediatric patients with cancer and fever in neutropenia. Journal of the Pediatric Infectious Diseases Society, 2 (2) pit005, 155-161. doi: 10.1093/jpids/pit005

Cestari, Igor, Evans-Osses, Ingrid, Schlapbach, Luregn J., de Messias-Reason, Iara and Ramirez, Marcel I. (2013). Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites. Molecular Immunology, 53 (4), 328-334. doi: 10.1016/j.molimm.2012.08.015

Schlapbach, Luregn J., Woerner, Andreas, Thiel, Steffen, Ammann, Roland A., Aebi, Christoph, Nelle, Mathias and Jensenius, Jens C. (2013). Good agreement between capillary and venous sampling for lectin pathway proteins. Immunobiology, 218 (4), 465-469. doi: 10.1016/j.imbio.2012.06.001

Schlapbach, Luregn J., Graf, Rolf, Woerner, Andreas, Fontana, Matteo, Zimmermann-Baer, Urs, Glauser, David, Giannoni, Eric, Roger, Thierry, Muller, Christoph, Nelle, Mathias and Stocker, Martin (2013). Pancreatic stone protein as a novel marker for neonatal sepsis. Intensive Care Medicine, 39 (4), 754-763. doi: 10.1007/s00134-012-2798-3

Schlapbach, Luregn J., Grips, Martin, Justo, Rob and Karl, Tom (2012). Extracorporeal membrane oxygenation as a bridge to diagnosis in a 20-month old girl with pulmonary hypertension and right ventricular failure. Interactive Cardiovascular and Thoracic Surgery, 15 (6), 1088-1089. doi: 10.1093/icvts/ivs401

Schlapbach, Luregn J., Adams, Mark, Proietti, Elena, Aebischer, Maude, Grunt, Sebastian, Borradori-Tolsa, Cristina, Bickle-Graz, Myriam, Bucher, Hans Ulrich, Latal, Beatrice and Natalucci, Giancarlo (2012). Outcome at two years of age in a Swiss national cohort of extremely preterm infants born between 2000 and 2008. Bmc Pediatrics, 12 (1) 198, 198.1-198.12. doi: 10.1186/1471-2431-12-198

Schlapbach, Luregn J., Schibler, Andreas and Jensenius, Jens C. (2012). C1-esterase inhibitor treatment in sepsis-Can we target the right patients?. Critical Care Medicine, 40 (9), 2735-2736. doi: 10.1097/CCM.0b013e318258eb7a

Schlapbach, Luregn J., Kjaer, Troels R., Thiel, Steffen, Mattmann, Maika, Nelle, Mathias, Wagner, Bendicht P., Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2012). M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis. Pediatric Research, 71 (4), 368-374. doi: 10.1038/pr.2011.71

Schlapbach, Luregn J., Thiel, Steffen, Kessler, Ulf, Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2011). Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitis. Gut, 60 (10), 1438-1439. doi: 10.1136/gut.2010.226027

Schlapbach, L. J., Frey, S., Roger, T., Calandra, T., Nelle, M., Aebi, C. and Giannoni, E. (2011). Umbilical venous concentrations of estradiol in infants with early-onset sepsis and chorioamnionitis. Journal of Neonatal-Perinatal Medicine, 4 (2), 147-154. doi: 10.3233/NPM-2011-2739

Schlapbach, Luregn J., Frey, Stefanie, Bigler, Susanna, Manh-Nhi, Chiem, Aebi, Christoph, Nelle, Mathias and Nuoffer, Jean-Marc (2011). Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia. BMC Pediatrics, 11 (1) 38, 38.1-38.8. doi: 10.1186/1471-2431-11-38

Pramana, I. A., Latzin, P., Schlapbach, L. J., Hafen, G., Kuehni, C. E., Nelle, M., Riedel, T. and Frey, U. (2011). Respiratory symptoms in preterm infants: burden of disease in the first year of life. European Journal of Medical Research, 16 (5), 223-230. doi: 10.1186/2047-783X-16-5-223

Schlapbach, Luregn J., Thiel, Steffen, Aebi, Christoph, Hirt, Andreas, Leibundgut, Kurt, Jensenius, Jens C. and Ammann, Roland A. (2011). M-ficolin in children with cancer. Immunobiology, 216 (5), 633-638. doi: 10.1016/j.imbio.2010.09.013

Fischa, Urs P., Zehndera, Aina, Hirta, Andreas, Nigglib, Felix K., Simonc, Arne, Ozsahind, Hulya, Schlapbacha, Luregn J. and Ammanna, Roland A. (2011). Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer. Swiss Medical Weekly, 141 (APRIL), w13191. doi: 10.4414/smw.2011.13191

Schlapbach, Luregn Jan, Agyeman, Philipp, Hutter, Damian, Aebi, Christoph, Wagner, Bendicht Peter and Riedel, Thomas (2011). Human metapneumovirus infection as an emerging pathogen causing acute respiratory distress syndrome. Journal of Infectious Diseases, 203 (2), 294-295. doi: 10.1093/infdis/jiq045

Sallenbach, Seraina, Thiel, Steffen, Aebi, Christoph, Otth, Margrith, Bigler, Susanna, Jensenius, Jens C., Schlapbach, Luregn J. and Ammann, Roland A. (2011). Serum Concentrations Of Lectin-Pathway Components In Healthy Neonates, Children And Adults: Mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2). Pediatric Allergy and Immunology, 22 (4), 424-430. doi: 10.1111/j.1399-3038.2010.01104.x

Schlapbach, Luregn J., Mattmann, Maika, Thiel, Steffen, Boillat, Colette, Otth, Margrith, Nelle, Mathias, Wagner, Bendicht, Jensenius, Jens C. and Aebi, Christoph (2010). Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis. Clinical Infectious Diseases, 51 (2), 153-162. doi: 10.1086/653531

Schlapbach, Luregn Jan, Riedel, Thomas, Genitsch, Vera, Nelle, Mathias and McDougall, Felicity Jane (2010). Fatal pulmonary embolism in a premature neonate after twin-to-twin transfusion syndrome. Pediatrics, 126 (2), E483-E487. doi: 10.1542/peds.2009-3490

Schlapbach, Luregn J., Ersch, Jörg, Adams, Mark, Bernet, Vera, Bucher, Hans Ulrich and Latal, Beatrice (2010). Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age. Acta Paediatrica, International Journal of Paediatrics, 99 (10), 1504-1509. doi: 10.1111/j.1651-2227.2010.01861.x

Zehnder, Aina, Fisch, Urs, Hirt, Andreas, Niggli, Felix K., Simon, Arne, Ozsahin, Hulya, Schlapbach, Luregn J. and Ammann, Roland A. (2009). Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2). Pediatric Blood and Cancer, 53 (1), 53-57. doi: 10.1002/pbc.22028

Schlapbach, Luregn Jan, Pfammatter, Jean-Pierre, Nelle, Mathias and McDougall, Felicity Jane (2009). Cardiomegaly in a premature neonate after venous umbilical catheterization. European Journal of Pediatrics, 168 (1), 107-109. doi: 10.1007/s00431-008-0704-3

Schlapbach, Luregn Jan, Latzin, Philipp, Regamey, Nicolas, Kuehni, Claudia E., Zwahlen, Marcel, Casaulta, Carmen, Aebi, Christoph and Frey, Urs (2009). Mannose-binding lectin cord blood levels and respiratory symptoms during infancy: A prospective birth cohort study. Pediatric Allergy and Immunology, 20 (3), 219-226. doi: 10.1111/j.1399-3038.2008.00782.x

Schlapbach, Luregn J., Kessler, Ulf, Thiel, Steffen, Hansen, Annette G., Nelle, Mathias, Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2009). M-ficolin in the neonatal period: associations with need for mechanical ventilation and mortality in premature infants with necrotising enterocolitis. Molecular Immunology, 46 (13), 2597-2603. doi: 10.1016/j.molimm.2009.05.003

Schlapbach, L. J., Aebi, C., Hansen, A. G., Hirt, A., Jensenius, J. C. and Ammann, R. A. (2009). H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients. Clinical and Experimental Immunology, 157 (1), 83-89. doi: 10.1111/j.1365-2249.2009.03957.x

Schlapbach, Luregn J., Aebi, Christoph, Fisch, Urs, Ammann, Roland A., Otth, Margrith, Bigler, Susanne, Nelle, Mathias, Berger, Steffen and Kessler, Ulf (2008). Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis. Pediatric Research, 64 (5), 562-566. doi: 10.1203/PDR.0b013e3181841335

Schlapbach L.J., Schutz B., Nuoffer J.-M., Brekenfeld C., Muller G. and Fluri S. (2007). Floppy infant with macrocytic anemia and vegan mother. Praxis, 96 (35), 1309-1314. doi: 10.1024/1661-8157.96.35.1309

Schlapbach, L. J., Aebi, C., Otth, M., Luethy, A. Ridolfi, Leibundgut K., Hirt A. and Ammann R.A. (2007). Serum levels of mannose-binding lectin and the risk of fever in neutropenic pediatric cancer patients. Pediatric Blood and Cancer, 49 (1), 11-16. doi: 10.1002/pbc.21097

Schlapbach L.J., Aebi C., Otth M., Leibundgut K., Hirt A. and Ammann R.A. (2007). Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients. Pediatric Infectious Disease Journal, 26 (11), 989-994. doi: 10.1097/INF.0b013e31811ffe6a

Schlapbach L., Liniger B., Schibli S. and Cholewa D. (2006). A small child with acute abdomen and iron deficiency anemia. Praxis, 95 (22), 913-916. doi: 10.1024/0369-8394.95.22.913

Schlapbach L.J., Sozzo A., Ramelli G. and Bianchetti M.G. (2006). Severe normotensive metabolic alkalosis in a 2-month-old boy with hyperekplexia. Journal of Inherited Metabolic Disease, 29 (1), 238-239. doi: 10.1007/s10545-006-0082-9

Hess C., Klimkait T., Schlapbach L., Del Zenero V., Sadallah S., Horakova E., Balestra G., Werder V., Schaefer C., Battegay M. and Schifferli J.-A. (2002). Association of a pool of HIV-1 with erythrocytes in vivo: A cohort study. Lancet, 359 (9325), 2230-2234. doi: 10.1016/S0140-6736(02)09291-7

Schlapbach, L. (2018). Time for Sepsis-3 in kids? - Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.aucc.2017.12.026

Schlapbach, L. (2018). Time for Sepsis-3 in kids? Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.aucc.2017.12.005

Schlapbach, Luregn, Straney, Lahn, Gelbart, Ben, Alexander, Janet, Franklin, Donna, Beca, John, Whitty, Jennifer, Ganu, Subodh, Wilkins, Barry, Slater, Anthony, Croston, Elizabeth, Erickson, Simon and Schibler, Andreas (2017). Burden of disease and change in practice in critically ill infants with bronchiolitis in Australia and New Zealand 2002 to 2014. 41st Australian and New Zealand Scientific Meeting on Intensive Care, Perth WA, Australia, 20-22 October 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2017.02.067

Schlapbach, L. J., Straney, L., Gelbart, B., Alexander, J., Franklin, D., Beca, J., Whitty, J. A., Ganu, S., Wilkins, B., Croston, E., Erickson, S. and Schibler, A. (2016). Burden of Disease and Change in Practice in Critically Ill Infants with Bronchiolitis in Australia and New Zealand 2002 to 2014. NEW YORK: SPRINGER. doi: 10.1016/j.aucc.2017.02.067

Schlapbach, L. J., Agyeman, P., Giannoni, E., Stocker, M., Posfay-Barbe, K., Heiningere, U., Schindler, M., Kuehni, C., Konetzny, G., Niederer-Loher, A., Kahlert, C., Hasters, P., Relly, C., Baer, W., Aebi, C. and Berger, C. (2016). Severe Sepsis with Bacteremia in Children in Switzerland - Results From the Swiss Pediatric Sepsis Study. NEW YORK: SPRINGER.

Sallenbach, S., Thiel. S., Aebi, C., Otth, M., Jensenius, J. C., Schlapbach, L. J. and Ammann, R. A. (2011). Age-specific normal ranges of lectin-pathway components in human serum: mannose-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2).. 23rd International National Complement Workshop, New York, New York, USA, 01-05 August 2010. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2010.05.069

Schlapbach, L. J., Thiel, S., Aebi, C., Hirt, A., Leibundgut, K., Jensenius, J. C. and Ammann, R. A. (2010). Serum M-ficolin in children with cancer. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.241

Schlapbach, L. J., Thiel, S., Mattmann, M., Nelle, M., Wagner, B., Ammann, R. A., Aebi, C. and Jensenius, J. C. (2010). M-ficolin serum concentrations are related to early-onset neonatal sepsis and circulating phagocytes. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.031

Schlapbach, L. J., Aebi, C., Nelle, M., Ammann, R. A., Berger, S. and Kessler, U. (2008). Elevated cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis - a case-control study. E M H SWISS MEDICAL PUBLISHERS LTD.

Schlapbach, L. J., Ammann, R. A., Hansen, A. Gudmann, Hirt, A., Jensenius, J. C. and Aebi, C. (2008). Serum concentration of H-ficolin and the risk of fever and neutropenia in pediatric cancer patients. E M H SWISS MEDICAL PUBLISHERS LTD.

Schlapbach, L. J., Latzin, P., Regamey, N., Kuehni, C. E., Zwahlen, M., Casaulta, C., Aebi, C. and Frey, U. (2007). Mannose-binding Lectin cord blood levels are associated with respiratory symptoms during infancy. E M H SWISS MEDICAL PUBLISHERS LTD.

Mohd Ali, Noor Azizah, Jauncey-Cooke, Jacqueline, Bogossian, Fiona, Schlapbach, Luregn and Chang, Ivy (2017). Ventilator-associated pneumonia and ventilator-associated events in PICU, LCCH. Paediatric Intensive Care, Lady Cilento Children's Hospital, The University of Queensland.

Associate Professor Luregn Schlapbach

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Seminar Paper